Principal Investigator
Takaaki Kuwajima, PhD
Research Assistant Professor of Ophthalmology
Universitry of Pittsburgh School of Medicine
Member of the Louis J. Fox Center for Vision Restoration
Lab Personnel
Dwarkesh Amin, Undergraduate Student
Gregory Campbell, Research Technician
Sneha Misra, Undergraduate Student
Research Interests
- Optic nerve regeneration
- Optic nerve degeneration
- Retinal axon injury
- Glaucoma
- Retinal axon development
Representative Publications
- Kuwajima T, Mason C (2017) Live or Die? Depends Who You Are Neuron 94 (6):1043-1045
- Kuwajima T**, Celia S, Sitko AA, Lefebvre V, Mason C** (2017) SoxC transcription factors promote contralateral retinal ganglion cell differentiation and axon guidance in the mouse visual system. Neuron 93 (5):1110-1125 [** corresponding authors]
- Li H, Kuwajima T, Oakley D, Nikulina E, Hou J, Yang WS, Lowry ER, Lamas NJ, Amoroso MW, Croft GF, Hosur R, Wichterle H, Sebti S, Filbin MT, Stockwell B, Henderson CE (2016) Protein prenylation constitutes an endogenous brake on axonal growth. Cell Reports 16(2):545-558
- Kuwajima T, Sitko AA, Bhansali P, Jurgens C, Guido W, Mason C (2013) ClearT: a detergent- and solvent-free clearing method for visualizing neuronal and non- neuronal tissues. Development 140 (6):1364-1368
- Kuwajima T, Yoshida Y, Takegahara N, Petros TJ, Kumanogoh A, Jessell TM, Sakurai, T, Mason C (2012) Optic chiasm presentation of Semaphorin6D in the context with Plexin-A1 and Nr-CAM promotes retinal axon midline crossing. Neuron 74 (4):676-690
- Kuwajima T*, Hasegawa K*, Yoshikawa K (2010) Necdin promotes tangential migration of neocortical interneurons from basal forebrain. Journal of Neuroscience 30 (10):3709-3714 [*equal contribution to this work]
- Kuwajima T, Nishimura I, Yoshikawa K (2006) Necdin promotes GABAergic neuron differentiation in cooperation with Dlx homeodomain proteins. Journal of Neuroscience 26 (20):5383-5392
Contact Information
Takaa Kuwajimi, PhD
BST3 10014A
Pittsburgh, PA 15213
kuwajima@pitt.edu
412-624-5432